Addition to Metalloglycosidase Mimics: Oxidative Cleavage of Saccharides Promoted by Multinuclear Copper Complexes under Physiological Conditions

Dinitrogen Binding and Cleavage by Multinuclear Iron Complexes

The iron-molybdenum cofactor of nitrogenase has unprecedented coordination chemistry, including a high-spin iron cluster called the iron-molybdenum cofactor (FeMoco). Thus, understanding the mechanism of nitrogenase challenges coordination chemists to understand the fundamental N2 chemistry of high-spin iron sites. This Account summarizes a series of studies in which we have synthesized a numbe...

evaluation of oxidative dna cleavage of copper (ii) complexes as chemotherapeutic agents

Lewis acid-promoted oxidative addition of thioimidates to Pd0.

The isomeric S-methyldihydropyrrins 9-Z and 9-E exhibit markedly different behavior in Pd(0)-catalyzed cross-coupling reactions. Thioimidates 9-Z are readily converted to imines 10-Z employing Pd(0)/AlkZnI. Under identical conditions 9-E are inert. Oxidative addition to Pd(0) requires activation by Zn or other Lewis acids, which is sterically unfavorable with 9-E. Analogous results were obtaine...

Physiological Response of Quinoa to Nitrogen Application under Salinity Conditions

Salinity stress is one of the major abiotic stresses which injures plants by limited water absorption and nutrient imbalance and limits crop growth. In order to study the effect of nitrogen fertilizer on physiological traits of quinoa at high salt concentrations, a greenhouse experiment was conducted in a factorial arrangement based on a randomized complete block with three replications in 2019...

Kinetics of Isomerization and Inversion of Aspartate 58 of αA-Crystallin Peptide Mimics under Physiological Conditions

Although proteins consist exclusively of L-amino acids, we have reported that aspartyl (Asp) 58 and Asp 151 residues of αA-crystallin of eye lenses from elderly cataract donors are highly inverted and isomerized to D-β, D-α and L-β-Asp residues through succinimide intermediates. Of these Asp isomers, large amounts of D-β- and L-β-isomers are present but the amount of D-α-isomer is not significa...